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. 2015 Apr 27;309(2):H369–H380. doi: 10.1152/ajpheart.00078.2015

Table 3.

Blood variable responses to exercise in the heated and cooled leg during systemic and leg heat stress combined with leg cooling (Study 1)

Exercise With Cooled Leg, W
Exercise With Heated Leg, W
Rest 12 ± 1 27 ± 1 39 ± 1 50 ± 3 Rest 12 ± 1 27 ± 1 39 ± 1 52 ± 2
Hb, g/l
    a 156 ± 8 152 ± 4 151 ± 4 154 ± 4 152 ± 6 152 ± 4 153 ± 4 150 ± 6 152 ± 4 157 ± 4
    vh 152 ± 4 152 ± 4 153 ± 4 152 ± 5 161 ± 3 150 ± 4 152 ± 5 149 ± 9 152 ± 6 152 ± 4
    vc 152 ± 4 150 ± 4 153 ± 3 152 ± 4 161 ± 4* 153 ± 4 150 ± 5* 153 ± 10 155 ± 4 156 ± 3
O2 saturation, %
    a 98 ± 0.2 98 ± 0.3 98 ± 0.2 98 ± 0.2 98 ± 0.2 98 ± 0.4 98 ± 0.2 98 ± 0.4 98 ± 0.2 98 ± 0.2
    vh 71 ± 4 61 ± 3 52 ± 4* 52 ± 4* 53 ± 5* 48 ± 6 43 ± 4 36 ± 4 28 ± 3* 27 ± 4*
    vc 59 ± 7 37 ± 4* 26 ± 2* 25 ± 3* 21 ± 3* 66 ± 6 59 ± 5 56 ± 3* 52 ± 4* 48 ± 4*
Po2, mmHg
    a 105 ± 6 103 ± 4 101 ± 2 106 ± 4 109 ± 3 111 ± 6 100 ± 3 110 ± 10 102 ± 2 105 ± 2
    vh 34 ± 1 34 ± 1 31 ± 1 32 ± 2 32 ± 2 30 ± 2 28 ± 2 26 ± 1 23 ± 1 23 ± 2
    vc 32 ± 4 23 ± 1* 20 ± 1* 20 ± 1* 20 ± 1* 38 ± 4 32 ± 2 31 ± 2 30 ± 2 29 ± 2
CtO2, ml/l
    a 200 ± 4 205 ± 4 204 ± 5 208 ± 4 207 ± 7 206 ± 5 206 ± 5 202 ± 7 205 ± 4 212 ± 5
    vh 138 ± 1 127 ± 1 110 ± 1* 108 ± 1* 116 ± 1* 99 ± 1 90 ± 1 75 ± 1* 59 ± 1* 58 ± 1*
    vc 127 ± 2 78 ± 1* 55 ± 0.3* 53 ± 0.4* 48 ± 1* 135 ± 2 111 ± 2* 112 ± 1* 110 ± 1* 100 ± 1*
Pco2, mmHg
    a 41 ± 1 40 ± 1 42 ± 1 39 ± 2 38 ± 2 36 ± 3 39 ± 2 36 ± 2 39 ± 2 38 ± 2
    vh 47 ± 1 49 ± 1 52 ± 1* 53 ± 1* 53 ± 2* 50 ± 2 55 ± 2* 59 ± 2* 64 ± 2* 71 ± 4*#
    vc 47 ± 3 56 ± 3* 65 ± 3* 73 ± 4* 80 ± 3* 43 ± 2 44 ± 2 46 ± 2* 48 ± 1* 50 ± 1*
pH
    a 7.42 ± 0.01 7.41 ± 0.01 7.39 ± 0.01 7.39 ± 0.01 7.40 ± 0.01 7.41 ± 0.03 7.40 ± 0.01 7.41 ± 0.02 7.39 ± 0.01 7.39 ± 0.01
    vh 7.39 ± 0.01 7.37 ± 0.01 7.36 ± 0.01* 7.35 ± 0.01* 7.34 ± 0.01* 7.36 ± 0.02 7.34 ± 0.01 7.31 ± 0.01* 7.29 ± 0.01* 7.25 ± 0.02*#
    vc 7.40 ± 0.01 7.33 ± 0.01* 7.29 ± 0.01* 7.25 ± 0.02* 7.21 ± 0.02* 7.36 ± 0.02 7.37 ± 0.02 7.36 ± 0.01 7.36 ± 0.01 7.35 ± 0.01
Glucose, mmol/l
    a 6.5 ± 0.4 6.6 ± 0.3 6.6 ± 0.2 6.4 ± 0.2 6.3 ± 0.2 6.6 ± 0.2 6.7 ± 0.3 6.8 ± 0.3 6.8 ± 0.4 6.8 ± 0.4
    vh 6.1 ± 0.3 6.1 ± 0.3 6.1 ± 0.2 6.1 ± 0.2 6.0 ± 0.3 6.1 ± 0.3 6.4 ± 0.5 6.3 ± 0.5 6.2 ± 0.6 6.1 ± 0.6
    vc 5.9 ± 0.2 6.2 ± 0.3 6.3 ± 0.2 6.1 ± 0.2 6.3 ± 0.3 5.9 ± 0.4 6.2 ± 0.3 6.4 ± 0.4 6.6 ± 0.4 6.6 ± 0.4
Lactate, mmol/l
    a 1.5 ± 0.3 1.7 ± 0.3 2.2 ± 0.3* 3.0 ± 0.5* 4.1 ± 0.7* 3.6 ± 0.9 3.4 ± 0.7 3.4 ± 0.7 4.0 ± 0.4 4.7 ± 0.5*
    vh 1.4 ± 0.2 1.4 ± 0.2 1.7 ± 0.2 2.2 ± 0.3* 3.3 ± 0.5* 2.9 ± 0.5# 3.4 ± 0.5# 3.5 ± 0.5* 4.0 ± 0.6* 5.3 ± 0.9*
    vc 1.4 ± 0.2 2.3 ± 0.3* 3.0 ± 0.4* 4.3 ± 0.6* 6.0 ± 0.8* 4.4 ± 0.9 3.5 ± 0.7 3.4 ± 0.5 3.3 ± 0.5 3.8 ± 0.5

Values are means ± SE for 7 participants (venous samples) and 6 participants (arterial samples). Po2, Pco2, and pH were corrected for changes in blood temperature.

*

Significantly different from baseline;

#

significantly different from cooled femoral venous blood during cooled leg exercise. P < 0.05.