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Concentration-response curves to acetylcholine (ACh) and sodium nitroprusside (SNP) in resistance mesenteric arteries from female Goto-Kakizaki (GK) and Wistar rats. A: arteries from GK type 2 diabetic rats (n = 13) had reduced responses to ACh compared with arteries from Wistar rats (n = 7) (*P < 0.05, Wistar vs. GK). B: arteries from GK type 2 diabetic rats (n = 14) had reduced responses to SNP compared with arteries from Wistar rats (n = 12) (*P < 0.05, Wistar vs. GK).
