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. 2015 May 26;290(29):17784–17795. doi: 10.1074/jbc.M115.655019

FIGURE 2.

FIGURE 2.

SFN activated Nrf2/HO-1 signaling pathway in normal BL10 mice. 4-week-old male C57/Black 10 mice were separately treated with SFN (2 mg/kg of body weight by gavage), and 4-week-old C57/Black 10 mice were treated with corn oil in the same dose for 4 weeks. Then mice were sacrificed, and related muscles were collected. A, Western blot of Nrf2 and HO-1 protein in TA muscles. B, statistical analysis of Western blot of Nrf2 and HO-1 protein. C, qRT-PCR of Nrf2 and HO-1 genes in TA muscles. Data are the means ± S.E. (error bars) of three independent experiments. *, p < 0.05 versus BL10 mice. n = 6 for each group. Statistical analysis was conducted using Student's t test.