TABLE 4.
Incidence of malaria cases in children whose piperaquine concentration in plasma was measured in capillary samples on day 7
| Piperaquine concn (ng/ml) |
No. of: |
Person-months at risk | Rate (no./month) | Ratio (95% CI) | ||
|---|---|---|---|---|---|---|
| Mean (SD) | Range | Children | Malaria cases | |||
| 27.7 (8.40) | 7.4–40.5 | 53 | 10 | 78.81 | 0.127 | 1 |
| 50.4 (6.14) | 40.6–63.0 | 53 | 8 | 94.55 | 0.085 | 0.67 (0.23–1.9) |
| 85.2 (21.8) | 63.1–163 | 53 | 4 | 99.11 | 0.040 | 0.32 (0.07–1.1) |