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. 2015 Jul 16;59(8):4882–4888. doi: 10.1128/AAC.00440-15

TABLE 1.

CC50s and CC90s of WPR-6, TNK651, and NVP for different cellsa

Cell type CC50, CC90 (μM)b
WPR-6 TNK-651 NVP
MT-4 98.3 ± 2.7, 286.2 ± 4.0 84.6 ± 1.5, 166.6 ± 1.7 >1,000, >1,000
PBMCs 137.8 ± 8.2, 297.6 ± 14.7 166.6 ± 1.7, 291.7 ± 6.0 >1,000, >1,000
TZM-bl 76.4 ± 5.7, 360.4 ± 14.2 65.8 ± 0.7, 115.8 ± 2.2 >1,000, >1,000
a

Each compound was tested in triplicate, and the data presented are mean values ± standard deviations from at least two independent experiments.

b

The XTT assay was used to determine CC50s and CC90s.