TABLE 1.
CC50s and CC90s of WPR-6, TNK651, and NVP for different cellsa
Cell type | CC50, CC90 (μM)b |
||
---|---|---|---|
WPR-6 | TNK-651 | NVP | |
MT-4 | 98.3 ± 2.7, 286.2 ± 4.0 | 84.6 ± 1.5, 166.6 ± 1.7 | >1,000, >1,000 |
PBMCs | 137.8 ± 8.2, 297.6 ± 14.7 | 166.6 ± 1.7, 291.7 ± 6.0 | >1,000, >1,000 |
TZM-bl | 76.4 ± 5.7, 360.4 ± 14.2 | 65.8 ± 0.7, 115.8 ± 2.2 | >1,000, >1,000 |
Each compound was tested in triplicate, and the data presented are mean values ± standard deviations from at least two independent experiments.
The XTT assay was used to determine CC50s and CC90s.