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. 2015 Jul 16;59(8):4577–4583. doi: 10.1128/AAC.05064-14

FIG 1.

FIG 1

Schematic presentation of the orfX downstream region in the M. caseolyticus KM45013 chromosome, including the novel SCCmecKM45013 (ENA accession no. HG970732), and a comparison with the previous mecB-carrying genetic structures detected in macrococci: M. caseolyticus strain JCSC7528 (GenBank accession no. AB498758), JCSC5402 (GenBank accession no. AP009486), and JCSC7096 (GenBank accession no. AB498756) and their correspondent chromosomal orfX downstream regions (GenBank accession no. AB498757, AP009484, and AB498756, respectively). The arrows indicate the extent and direction of transcription of the open reading frames. All annotated regions of M. caseolyticus KM45013 are colored as follows: yellow (orfX), pale pink (tnp), pale green (ccrAm, ccrBm), dark green (mecIm), green (mecRm), red (mecB, mecAm), blue (blaZm), purple (orf46), pale purple (orf51), magenta (MCCL_0033) and pink (MCCL_0034). The different integration site sequences (ISSs) for SCC (ISS1 to ISS4) are shown within boxes. The direct repeats (CTGAA) of transposon Tn6045 in strains JCSC7528, JCSC5402, and JCSC7096 are shown within dashed boxes. Shadowed areas indicate regions with more than 84% nucleotide sequence identity. Tn6045 in strains JCSC7528, JCSC5402, and JCSC7096 (green horizontal curly brackets) and the joining regions J1 to J3 (red horizontal bar) in KM45013 are also shown. B and Bg indicate the BamHI and BglII restriction sites, respectively, within SCCmecKM45013. A size scale in kb is displayed in the upper right-hand corner.