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Representative time-kill studies of 6″-thioether TOB analogues with C12 and C14 linear alkyl chains against azole-resistant C. albicans ATCC 64124 (strain B). (a) Cultures were exposed to C12 at 8, 16, or 32 mg/liter. (b) Cultures were exposed to C14 at 2, 4, or 8 mg/liter. In both panels, cultures were exposed to FLC at 16 mg/liter and AmB at 1 mg/liter or to a no-drug control.
