TABLE 3.
Triazole | ΔA max | λtrough | λpeak | Kd (μM) | Hill no. | [Azole]0.5 (μM) |
---|---|---|---|---|---|---|
FLC | 0.048 | 410 | 428 | 0.074 (± 0.015) | 3.0 | 0.43 |
VCZ | 0.051 | 410 | 428 | 0.082 (± 0.018) | 2.7 | 0.4 |
The binding of azole drugs to 1 μM Ni-NTA affinity-purified ScErg11p6×His was determined as described in Materials and Methods. max, maximum. Standard errors are shown in parentheses.