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. 2015 Jul 16;59(8):4616–4624. doi: 10.1128/AAC.00864-15

FIG 4.

FIG 4

Killing of B. burgdorferi with drug combinations. (a) Time-dependent killing of late exponential B. burgdorferi cultures exposed to the indicated antibiotics in combination. Amoxicillin (Amox) (6 μg/ml), ceftriaxone (Cef) (3 μg/ml), and doxycycline (Dox) (2.5 μg/ml) (n = 6). (b) Killing of late exponential B. burgdorferi exposed to gemifloxacin (Gemi) (1.5 μg/ml) and/or spectinomycin (Spec) (160 μg/ml) singly or in combination (n = 6). An aliquot was taken at indicated time points, washed, diluted, and plated on semisolid BSK-II medium for CFU counts. Error bars represent standard errors.