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. 2015 Jul 16;59(8):4551–4559. doi: 10.1128/AAC.05048-14

TABLE 1.

Summary of the bactericidal effects of olanexidine against various bacterial strains by exposure time and MBCa

Strain tested (no. of strains) Exposure time (s) Minimal bactericidal concn (range) (μg/ml) for:
Olanexidine gluconate Chlorhexidine digluconate Povidone-iodine
Gram-positive cocci except Enterococcus spp. (21) 30 13.6 to 1,740 39.1 to >2,500 ≤48.8 to 781
60 ≤6.8 to 869 9.8 to >2,500 ≤48.8 to 781
180 ≤6.8 to 434 9.8 to >1,250 ≤48.8 to 391
Enterococcus spp. (34) 30 13.6 to 434 5,000 to >5,000 195 to >50,000
60 ≤6.8 to 217 78.1 to >5,000 97.7 to >50,000
180 ≤6.8 to 54.3 9.8 to >5,000 ≤48.8 to 1,560
Gram-positive bacilli (9) 30 ≤6.8 to 1,740 19.5 to >2,500 97.7 to 781
60 ≤6.8 to 1,740 19.5 to >2,500 ≤48.8 to 781
180 ≤6.8 to 109 9.8 to >2,500 97.7 to 781
Gram-negative strains except Burkholderia cepacia (34) 30 ≤6.8 to 869 39.1 to >5,000 ≤48.8 to 3,130
60 ≤6.8 to 434 19.5 to >5,000 ≤48.8 to 781
180 ≤6.8 to 54.3 ≤4.9 to 2,500 ≤48.8 to 781
B. cepacia (2) 30 >6,950 >5,000 391
60 1,740 to >6,950 >5,000 391
180 434 625 195
a

The full data set is given in Table S1 in the supplemental material.