TABLE 3.
MICs of ceftaroline-avibactam for the new colonizing bacteria in volunteers receiving ceftaroline-avibactama
| Bacteria | No. of volunteers | MIC (mg/liter) |
|---|---|---|
| Enterococcus faecium | 5 | 0.5–8 |
| Enterococcus faecalis | 4 | 1–8 |
| Enterococcus durans | 1 | 1 |
| Alpha-hemolytic streptococci | 2 | 4 |
| Streptococcus salivarius | 2 | 1–4 |
| Enterobacter cloacae | 1 | 8 |
| Bacillus spp. | 1 | 4 |
| Acinetobacter baumannii | 1 | 4 |
| Stenotrophomonas maltophilia | 1 | 64 |
| Micrococcus spp. | 1 | 4 |
| Pseudomonas aeruginosa | 1 | 1 |
| Clostridium spp. | 7 | 1–128 |
| Lactobacillus spp. | 8 | 1–128 |
| Anaerobic Gram-positive rods | 6 | 1–16 |
a
Ceftaroline-avibactam administered as 600 mg ceftaroline fosamil and 600 mg avibactam i.v. over 1 h every 8 h on days 1 to 6 and a single dose on day 7.