FIG 5.
In vivo results following one (A and B) and two (C and D) courses (21 days) of treatment with 25 mg/kg rifampin twice daily. The parental strain IDRL-6169 was used to establish infections. Shown are the bacterial loads recovered from control (saline) animals (⬥) and treated (rifampin) animals (▲). (A and C) Results of quantitative cultures of bone. (B and D) Results of quantitative cultures of wire. Log10 CFU/g and CFU/cm2 values reported are from growth on blood agar plates without rifampin. The horizontal bars indicate the median values.