FIGURE 6.

Validation of the model structures. Comparison of the distance distributions obtained from the EPR experiments for the singly-labeled IKKγ (magenta lines) with the predicted distance distributions (blue lines) using a rotamer library approach for the 0–6 register models. The cumulative sum of the squares of the differences between the experimental and predicted distributions is used to provide a metric for goodness of fit (yellow lines). The background has been gray-shaded according to the relative final amplitude of the yellow lines: a white background implies perfect match, whereas a black background implies poor agreement.