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Effects of Hc-CATH on pro-inflammatory cytokines transcription and production induced by LPS. A, TNF-α mRNA. B, TNF-α production. C, IL-1β mRNA. D, IL-1β production. E, IL-6 mRNA. F, IL-6 production. G, effects of sHc-CATH, Hc-CATH1 and -2 on LPS-induced pro-inflammatory cytokines production. LPS, 100 ng/ml; peptides, 4 μg/ml. Data are mean ± S.E. values from three separate experiments. *, p < 0.05; **, p < 0.01 (significantly different compared with the control).
