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. 2015 May 27;290(27):16894–16905. doi: 10.1074/jbc.M114.627455

FIGURE 3.

FIGURE 3.

eNH4Cl-dependent inward currents when holding [NH3]o constant in SLC4A11-PS120. A, sample current trace in response to 0.17 mm NH3 at pHo 6.5, 7.5, and 8.5 in SLC4A11-PS120 cells. Current amplitude is similar across three pH solutions, with slightly larger current in pH 6.5 and slightly smaller current at pH 8.5. B, bar graph summary of NH3/H+ maximum current density at pH 6.5, 7.5, and 8.5 after a 40-s exposure to NH4Cl. Current density shows small differences under the three pH conditions, largest in pH 6.5 NH3 and smallest in pH 8.5 (n = 3, repeated measure ANOVA, p = 0.001; pairwise comparison pH 6.5 versus pH 7.5, p = 0.022; pH 7.5 versus pH 8.5, p = 0.051; pH 6.5 versus pH 8.5, p = 0.012). Error bars, S.E. *, p < 0.05.