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Activity of Chicago Sky Blue in cell-based assays. A, reduction in PrPSc in PK1 cells chronically infected with RML prions following 3 days of treatment with Chicago Sky Blue. conc, concentration. B, inhibition of the interaction of Aβ oligomers with COS-7 cells overexpressing mouse PrP. Data are the mean ± S.E. of four independent experiments. AU, arbitrary units.
