FIGURE 7.

A, production of IL-12p70; B, IL-17 producing CD4⁺ T cells; and C, IL-6 in the culture supernatant from DC only □ or co-cultured CD4⁺ T cell supernatant ■ (n = 3–5). For induction of IL-17 producing cells co-cultures of CD4⁺ T cells and stress agent-treated DC were treated with anti-CD3 and CD28 antibodies, followed by PMA and ionomycin, stress-treated DC-mediated IL-6R up-regulation (D) and representative flow cytometry of IL-6R expression in CD4⁺ T cells (E). As, sodium arsenite; Gr, gramicidin; DITH, dithiocarbamate.