TABLE 2.
Microarray analysis of CD4+CD45RO+ memory T cells
These cells were tested from 3 subjects by the Illumina platform following co-culture of PBMC with gramicidin-treated DC and validated by the Affymetrix platform with cells from 3 other subjects. Group 1B consists of 10 IFN-stimulated genes which were also subjected to methylation inhibition by MTA.
| Group 1B genes (n = 10) | Interferon-stimulated genes |
||
|---|---|---|---|
| Illumina p < 0.05 | Affymetrix | MTA | |
| IF144L | 2.0 | 4.2 | −3.4 |
| IFIT1 | 2.3 | 5.2 | −3.0 |
| IFIT2 | 1.9 | 3.5 | −2.0 |
| ISG15 | 2.3 | 2.1 | −1.2 |
| IFI44 | 2.2 | 1.7 | +1.4 |
| IFI27 | 3.3 | 6.8 | −9.7 |
| RSAD2 | 2.2 | 2.0 | −4.8 |
| HERC5 | 1.9 | 2.2 | −1.7 |
| ID01 | 2.3 | 1.9 | −8.6 |
| BST2 | 3.3 | −1.3 | |