Skip to main content
. 2015 May 5;290(25):15855–15865. doi: 10.1074/jbc.M115.656181

FIGURE 7.

FIGURE 7.

Changes in single channel current amplitude in unmodified and modified channels. A, mean unitary current amplitude at −50 mV as a fraction of that in Cys-less CFTR. Asterisks indicate a significant difference from Cys-less (p < 0.00001). B, mean effect of MTSES on unitary current amplitude at −50 mV. C, mean effect of MTSET on unitary current amplitude at −50 mV. In B and C, asterisks indicate a significant difference from current amplitude in the same channel variant in the absence of MTS reagent (p < 0.0001). In each panel, error bars represent the means ± S.E. from 3–10 patches.