TABLE 1.

The asymptotic amplitude and rate of non-oxidative release for disulfide oxidoreductases are inversely correlated with the redox potential of the enzyme

The amplitude and rate of non-oxidative release were obtained from the exponential fit parameters of the data in (Fig. 5C). Redox potentials were obtained from Refs. 39–41. A more negative redox potential indicates a lower intrinsic affinity for electrons and thus a lower oxidizing potency.

Enzyme	Amplitude of non-oxidative release	Rate of non-oxidative release	Redox potential
		s−1	mV
Thioredoxin	1.0	Faster than detection limit	− 230
PDI	0.84 ± 0.11	0.10 ± 0.03	−175
DsbA	0.44 ± 0.04	0.07 ± 0.02	−89