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IC50 (μg/ml) of various antibiotics for C. glutamicum wild-type and ΔltsA strains
The IC50 value corresponds to the drug concentration for which 50% inhibition of bacterial cell growth is observed. Each value is the mean of at least three independent experiments and is given ± S.D.
| Wild type (ATCC 13032) | ΔltsA | |
|---|---|---|
| Chloramphenicol | 2.6 ± 0.4 | 1.4 ± 0.4 |
| Ampicillin | 6.0 ± 0.1 | 0.24 ± 0.04 |
| Carbenicillin | 2.3 ± 0.2 | 0.23 ± 0.06 |
| Ceftazidim | 27 ± 3.6 | 0.10 ± 0.03 |
| Imipenem | 0.038 ± 0.001 | 0.0080 ± 0.0001 |
