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. 2015 Apr 13;290(21):13250–13262. doi: 10.1074/jbc.M114.634568

FIGURE 2.

FIGURE 2.

Sexually dimorphic metabolic responses to high fat diet feeding in mice. Shown are fasting glucose (A) and insulin levels (B) assessed at 4 weeks of diet challenge and 10 weeks of diet challenge (C). Shown is glucose tolerance testing in male and female mice after 12 weeks of diet feeding in ND (D) and HFD feeding (E). 16-week-fed glucose (F) and insulin (G) are shown. Shown are H&E images of livers after 6 weeks (H) and 16 weeks (I) of HFD. n = 4; *, p < 0.05; **, p < 0.01; ***, p < 0.005; ***, p < 0.001. Comparisons between sexes are shown as follows: #, p < 0.05; ##, p < 0.01; ###, p < 0.005; ####, p < 0.001. Error bars, S.E.