Elevated cytoplasmic levels of anillin cause change in cell shape.
A, microgrpahs of HeLa cells transiently expressing different GFP-anillins and staining with phalloidin to show actin organization and cell shape. White arrows indicate transfected cells. B, schematic outlining the different cell parameters measured to define changes in cell shape. a, cell width; b, cell length. C, quantitation of the ratio of cell width to cell length, outlined in B, in HeLa cells expressing different GFP-anillins. Error bars indicate ± S.E.