TABLE 5.
DEGs related to |log2| > 10 in PGCs versus SSCs of RNA-seq
| Gene identification | Description | log2 (PGCs vs. SSCs) | Regulation | p value | FDR | Function | Reference |
|---|---|---|---|---|---|---|---|
| XM_429858.1 | LOC421502 | 11.21551 | Up | 2.7E-286 | 3.9E-285 | ||
| XM_416467.2 | SMC1B | 10.64341 | Up | 0 | 0 | Required for chromatid cohesion and DNA recombination during meiosis and mitosis | Ref. 57 |
| XM_427005.2 | AAK1 | 10.14017 | Up | 4.61E-20 | 1.14E-19 | Reported as a positive regulator of the Notch pathway | Ref. 58 |
| NM_205030.1 | AMH | 10.04345 | Up | 0 | 0 | Prevents the development of the Müllerian ducts into the uterus and other Müllerian structures; regulates production of sex hormones | Refs. 34 and 35 |
| XM_428866.1 | S-KER | −10.7443 | Down | 4.09E-54 | 1.61E-53 |