TABLE 6.
DEGs related to |log2| > 10 in ESCs versus SSCs of RNA-seq
| Gene identification | Description | log2 (ESCs/SSCs) | Regulation | p value | FDR | Function | References |
|---|---|---|---|---|---|---|---|
| XM_422203.2 | LOC424360 | 11.05914 | Up | 9.10E-245 | 7.40E-244 | ||
| NM_001039453.1 | AQP1 | 11.01037 | Up | 1.20E-141 | 6.30E-141 | ||
| XM_421648.2 | PBIP | 10.53929 | Up | 0 | 0 | Induces endochondral bone formation in adult animals | Ref. 59 |
| NM_213579.1 | GEM | 10.53732 | Up | 0 | 0 | Regulation of Ca2+ channel expression at the cell surface | Ref. 60 |
| XM_419553.2 | LOC421508 | 10.52041 | Up | 0 | 0 | Defective regulation in failing hearts | Ref. 61 |
| XM_001232973.1 | LCAT | 10.51207 | Up | 4.39E-22 | 1.00E-21 | ||
| NM_204897.1 | MENT-1 | 10.43276 | Up | 0 | 0 | Associated with intranuclear foci of condensed chromatin | Ref. 62 |
| NM_204679.1 | CDERMO-1 | 10.21531 | Up | 1.60E-103 | 7.00E-103 | A role during avian skin and feather development | Ref. 63 |
| XM_427005.2 | AAK1 | 10.14017 | Up | 4.94E-19 | 1.08E-18 | Reported as a positive regulator of the Notch pathway | Ref. 58 |
| NM_205259.2 | LOC396194 | 10.11269 | Up | 1.24E-91 | 5.13E-91 | ||
| XM_426613.2 | LOC429057 | 10.1068 | Up | 0 | 0 | Regulates the function of the alternative complement pathway in fluid phase and on cellular surfaces | Ref. 64 |
| NM_001030541.1 | POSTN | 10.09206 | Up | 0 | 0 | Periostin as a mediator of matrix remodeling by cushion mesenchyme towards a mature valve structure | Ref. 65 |
| NM_204311.1 | CDX2 | −12.264 | Down | 0 | 0 | Critical for establishing the trophoectoderm, the precursor of the placenta | Ref. 66 |
| XM_415985.2 | LOC417741 | −10.6646 | Down | 3.10E-160 | 1.80E-159 | Encodes a secreted antagonist of Wnt signaling likely involved in inhibiting Xwnt8 and XmyoD ventrally | Ref. 67 |
| XM_001231344.1 | LOC768589 | −10.5428 | Down | 1.20E-107 | 5.30E-107 | Prevents apoptotic cell death | |
| XM_001234907.1 | LOC771651 | −10.3586 | Down | 4.05E-11 | 7.60E-11 |