TABLE 7.
DEGs related to |log2| > 10 in ESCs versus PGCs of microarray and RNA-seq
LHRH, luteinizing hormone-releasing hormone.
| Gene identification | Description | Function | References |
|---|---|---|---|
| NM_205335.2 | Gallus gallus transthyretin (TTR), mRNA | Transports thyroxine from the bloodstream to the brain | |
| NM_206989.1 | Gallus gallus prepro-urotensin II-related peptide (LOC404534), mRNA | Induces phenotypic differentiation, migration, and collagen synthesis | Ref. 53 |
| XM_001236989.1 | PREDICTED: Gallus gallus hypothetical protein LOC773980 (LOC777548), partial mRNA | Required for the correct speed and extent of migration | Ref. 27 |
| XM_426327.2 | PREDICTED: Gallus gallus similar to aminopeptidase A (LOC428771), mRNA | Probably plays a role in regulating growth and differentiation of early B-lineage cells | |
| NM_001001611.2 | Gallus gallus Gal 9 (GAL9), mRNA | GAL is a hypothalamic-hypophysiotropic hormone and is a neuromodulator of LHRH secretion and action | Ref. 21 and 22 |
| XM_414212.2 | PREDICTED: Gallus gallus hypothetical LOC415852 (LOC415852), mRNA | Regulating the responsiveness of cells to adrenal androgens | |
| XM_426984.2 | PREDICTED: Gallus gallus hypothetical LOC429428 (LOC429428), partial mRNA | Involved in the maintenance of the self-renewal of human ES cells by suppression of gene expression | Ref. 14 |
| NM_204675.1 | Gallus gallus wingless-type MMTV integration site family, member 3A (WNT3A), mRNA | Facilitates clonal plating of hESCs exhibiting functional hepatic differentiation | Ref. 56 |
| XM_001231344.1 | PREDICTED: Gallus gallus hypothetical protein LOC768589 (LOC768589), mRNA | Prevents apoptotic cell death | |
| XM_001234742.1 | PREDICTED: Gallus gallus similar to bactericidal/permeability-increasing protein-like 2 (LOC771461), mRNA | Plays an essential role in host defense | Ref. 55 |
| XM_416906.2 | PREDICTED: Gallus gallus hypothetical LOC418708 (LOC418708), mRNA | Responsible for the nucleosome structure of the chromosomal fiber in eukaryotes | |
| XM_430154.2 | PREDICTED: Gallus gallus hypothetical LOC424460 (LOC424460), mRNA | ||
| XM_414795.2 | PREDICTED: Gallus gallus similar to LOC398026 protein (LOC416488), mRNA | Required for normal fertility and fecundity | Ref. 16 |