Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Exp Physiol. 2015 Jun 15;100(7):776–795. doi: 10.1113/EP085066

Figure 2. Autonomic indices and cardiac function in young (10-12 wks), untreated and losartan-treated C57BL/6 and Sgcd−/− mice.

Figure 2

Panel A. Sgcd−/− mice exhibited severe autonomic dysfunction at a young age, which was prevented by treatment with losartan. Results from untreated (n = 5) and treated (n = 6) C57BL/6 mice, and untreated (n = 7) and treated (n = 6) Sgcd−/− mice are shown. *P<0.05, Sgcd−/− vs. C57BL/6 mice; †P<0.05, vs. untreated mice. Panel B. Left ventricular ejection fraction and end diastolic volume were not significantly different in Sgcd−/− vs. C57BL/6 mice, and were not affected by losartan treatment.