FIG 2.

Immunization schedule, antibody response induced by sE alone (reference group), and detection of passively administered MAbs (control groups). (A) Immunization schedule. C57BL/6 mice (five mice per group) were immunized three times (arrows above time line) intraperitoneally (i.p.) with sE alone, with sE in complex with MAb IC3, A3, or B4, or with MAbs alone. Blood samples were taken at different time points (arrows below time line). (B) Results of ELISAs (using sE as an antigen) of serum pools from the sE-immunized reference group (solid line) and from control groups with passively administered MAbs (dashed lines) at different time points after immunization.