FIG 2.
Production and response to type I IFN inhibition by tumor cells infected with M51R VSV. (a) IFN-β levels were measured by ELISA using supernatants taken from JSQ-3 or SQ20B cells 24 h after infection with M51R VSV at the indicated MOIs. Results are expressed as picograms/milliliter of IFN-β per 1 × 105 cells. The means ± SD from 3 individual experiments is shown. (b) Neutralizing antibodies to IFN-β, IFN-α, or a combination of the two antibodies were added to JSQ-3 cells 18 h prior to the addition of M51R VSV (MOI, 0.1) to the cultures. P values were determined by unpaired Student's t test.