FIG 7.

Long-term follow-up of viral load in macaques treated with ART-auranofin-BSO. Posttherapy viral loads are shown as circles. The posttherapy viral set points in the follow-up period after our previous publication (11) are shown by the brackets. Pretherapy viral set points are shown by the dashed horizontal lines and are based on all available measurements starting from 30 weeks before the initiation of ART. Both pre- and posttherapy viral set points are based on NASBA assay measurements (limit of detection, 50 copies of viral RNA/ml of plasma). Viral loads outside the brackets (not included in the analysis) are shown for clarity's sake and are aimed at aiding the reader in the historical understanding of the entire posttherapy follow-up. For macaque P157, the viral loads outside the brackets, and not included in the present analysis, were measured with a different technique (i.e., real-time PCR; limit of detection, 40 copies of viral RNA/ml of plasma [11]). The areas shaded in gray correspond to the periods in which a definition for elite control was applicable (25) and are characterized by an undetectable viral load set point.