FIG 14.
Effect of CD98hc and β1 integrin on HSV-1 replication. (A) sh-Luc-HEp-2, sh-β1 integrin-HEp-2, and sh-β1 integrin/β1 integrin-HEp-2 cells were infected with wild-type HSV-1(F) at an MOI of 0.05 (5 × 104 PFU/ml). At the indicated times postinfection, extracellular virus from cell culture supernatants were harvested and assayed. Each value is the mean ± the standard error of the results of three independent experiments. (B) Virus titers in panel A at 72 h postinfection. Each value is the mean ± the standard error of the results of three independent experiments. Statistical analysis was performed by one-way ANOVA and Tukey's test.