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Model of MHC-I upregulation during RSV infection of airway epithelial cells. The host senses invading RSV with RIG-I and initiates an antiviral response, including upregulation of antiviral genes and secretion of IFN-β, which in turn promotes NLRC5 expression and MHC-I upregulation. The “p” in red circles denotes phosphorylated proteins.
