FIG. 4.

Expression of CD169 on monocytes after CD8⁺ lymphocyte depletion during acute SIV infection. Ten SIV-infected macaques were treated with anti-CD8 antibody M-T807R1 during acute infection. (A) Monocyte CD169 mean fluorescence intensities in individual macaques after infection are plotted over time. (B) Plasma SIV viral loads in individual macaques after infection are shown. One animal with a low viral load (ER17, blue) and one with a high viral load (GN24, red) are highlighted. (C, D) Temporal association between CD8 T cell count and monocyte CD169 expression. (C) Monocyte CD169 mean fluorescence intensities and CD8 counts in individual macaques after infection are plotted together. (D) Mean values of CD169 mean fluorescence intensities and CD8 counts are plotted. Color images available online at www.liebertpub.com/aid