Table 2.
Essential Non-Homologous Proteins of C. jejuni with Results of Prioritization Analysis (Transmembrane and Cellular Location Prediction)
| No. | Gene name | Protein Id | Pathway involved | Protein existence | Subcellular location | TMHMM | 3D Exp | 3D Model | MW (Da) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | alr | Q9PP26 | D-Alanine metabolism; Vancomycin resistance | Inferred | Cytoplasmic | No | No | Yes | 37,256 |
| 2 | ddl | Q9PPC2 | D-Alanine metabolism; Vancomycin resistance; Peptidoglycan biosynthesis | Inferred | Cytoplasmic | No | No | Yes | 39,908 |
| 3 | lpxA | Q9PIM1 | Lipopolysaccharide biosynthesis | Predicted | Cytoplasmic | No | Yes | Yes | 28,651 |
| 4 | lpxD | Q9PHU0 | Lipopolysaccharide biosynthesis | Inferred | Unknown | No | No | Yes | 34,679 |
| 5 | lpxC | Q9PIZ5 | Lipopolysaccharide biosynthesis | Inferred | Cytoplasmic | No | No | Yes | 32,883 |
| 6 | murA | Q9PP65 | Peptidoglycan biosynthesis | Inferred | Cytoplasmic | No | No | Yes | 45,186 |
| 7 | murB | Q9PM01 | Peptidoglycan biosynthesis | Inferred | Cytoplasmic | No | No | Yes | 28,994 |
| 8 | murC | Q9PNN7 | Peptidoglycan biosynthesis | Inferred | Cytoplasmic | No | No | Yes | 48,372 |
| 9 | murF | Q0PA95 | Peptidoglycan biosynthesis; Vancomycin resistance | Predicted | Cytoplasmic Membrane | Yes | No | Yes | 55,234 |
| 10 | pbpA | Q0PB07 | Peptidoglycan biosynthesis; Beta-Lactam resistance | Predicted | Cytoplasmic Membrane | Yes | No | Yes | 72,628 |
| 11 | fba | Q0PAS0 | Methane metabolism; Biosynthesis of secondary metabolites; Microbial metabolism in diverse environments | Predicted | Cytoplasmic | No | Yes | Yes | 38,730 |
| 12 | aroQ | Q9PJ53 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 17,595 |
| 13 | pfs | Q0PC20 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 25,225 |
| 14 | panD | Q9PIK3 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | Yes | Yes | 13,974 |
| 15 | panC | Q9PIK2 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | Yes | Yes | 32,087 |
| 16 | panB | Q9PIK1 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 30,202 |
| 17 | pheA | Q0PBJ3 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 40,477 |
| 18 | aroE | Q0PBA5 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 29,978 |
| 19 | trpC | Q9PI11 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 29,573 |
| 20 | ispH | P0C632 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | No | 31,551 |
| 21 | aroA | P0C630 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 47,288 |
| 22 | aroB | Q9PNT2 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 39,596 |
| 23 | dxr | Q9PMV3 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 39,548 |
| 24 | Cj1370 | Q0P8N9 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 17,035 |
| 25 | aroC | Q9PM41 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | Yes | Yes | 39,252 |
| 26 | dapB | Q9PIT2 | Biosynthesis of secondary metabolites; Microbial metabolism in diverse environments | Inferred | Cytoplasmic | No | No | Yes | 26,696 |
| 27 | rpiB | Q0P9X4 | Biosynthesis of secondary metabolites; Microbial metabolism in diverse environments | Predicted | Cytoplasmic | No | No | Yes | 16,293 |
| 28 | pbpB | Q0PAZ1 | Peptidoglycan biosynthesis; Beta-Lactam resistance | Predicted | Cytoplasmic Membrane | Yes | No | Yes | 68,378 |
| 29 | pbpC | Q0PAL6 | Peptidoglycan biosynthesis; Beta-Lactam resistance | Predicted | Cytoplasmic Membrane | Yes | No | Yes | 67,971 |
| 30 | frdC | Q0PBA2 | Biosynthesis of secondary metabolites; Microbial metabolism in diverse environments; Two-component system | Predicted | Cytoplasmic Membrane | Yes | No | Yes | 30,028 |
| 31 | ccoP | Q0P8D0 | Two-component system | Inferred | Periplasmic | Yes | No | Yes | 31,162 |
| 32 | cheA | Q0PBM2 | Two-component system; Bacterial chemotaxis | Predicted | Cytoplasmic | No | No | Yes | 85,300 |
| 33 | cheV | Q0PBM1 | Two-component system; Bacterial chemotaxis | Predicted | Cytoplasmic | No | No | Yes | 35,858 |
| 34 | cheY | P0C635 | Two-component system; Bacterial chemotaxis | Inferred | Cytoplasmic | No | No | Yes | 14,437 |
| 35 | kdtA | Q0PAH2 | Lipopolysaccharide biosynthesis | Predicted | Cytoplasmic | Yes | No | Yes | 45,217 |
| 36 | gmhB | Q6TG07 | Lipopolysaccharide biosynthesis | Inferred | Cytoplasmic | No | No | Yes | 20,246 |
| 37 | waaC | Q0P9C1 | Lipopolysaccharide biosynthesis | Predicted | Cytoplasmic | No | No | Yes | 39,350 |
| 38 | Cj0462 | Q0PB51 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 39,759 |
| 39 | ubiD | Q0PAX0 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 69,160 |
| 40 | ispG | Q9PPM1 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 39,366 |
| 41 | Cj0837c | Q0PA53 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | No | 36,994 |
| 42 | hisH1 | Q0P8U2 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 22,699 |
| 43 | Cj1368 | Q0P8P1 | Biosynthesis of secondary metabolites | Predicted | Cytoplasmic | No | No | Yes | 41,278 |
| 44 | hisB | Q9PM76 | Biosynthesis of secondary metabolites | Inferred | Cytoplasmic | No | No | Yes | 39,580 |
| 45 | oorD | Q0PAY1 | Microbial metabolism in diverse environments | Predicted | Unknown | No | No | Yes | 11,443 |
| 46 | oorA | Q0PAY0 | Microbial metabolism in diverse environments | Predicted | Cytoplasmic | No | No | Yes | 41,052 |
| 47 | oorB | Q0PAX9 | Microbial metabolism in diverse environments | Predicted | Cytoplasmic | No | No | Yes | 31,208 |
| 48 | oorC | Q0PAX8 | Microbial metabolism in diverse environments | Predicted | Cytoplasmic | No | Yes | Yes | 20,097 |
| 49 | lysC | Q0PAT5 | Biosynthesis of secondary metabolites; Microbial metabolism in diverse environments | Inferred | Unknown | No | No | Yes | 42,676 |
| 50 | csrA | Q0P9F1 | Two-component system | Predicted | Unknown | No | No | Yes | 8,441 |
| 51 | Cj1153 | Q0P9A3 | Microbial metabolism in diverse environments; Two-component system | Predicted | Periplasmic | Yes | No | Yes | 10,838 |
| 52 | ccoN | Q0P8C7 | Two-component system | Inferred | Cytoplasmic Membrane | Yes | No | Yes | 55,888 |
| 53 | ccoQ | Q0P8C9 | Two-component system | Predicted | Unknown | Yes | No | No | 10,376 |
| 54 | fliE | Q9PHY8 | Flagellar assembly | Inferred | Unknown | No | No | No | 10,830 |
| 55 | flgA | Q0PAC1 | Flagellar assembly | Predicted | Cytoplasmic | No | No | Yes | 25,114 |
| 56 | flaD | Q0PA11 | Flagellar assembly | Predicted | Extracellular | No | No | Yes | 82,051 |
| 57 | flaB | P56964 | Two-component system; Flagellar assembly | Inferred | Extracellular | No | No | Yes | 59,186 |
| 58 | flaA | P56963 | Two-component system; Flagellar assembly | Inferred | Extracellular | No | No | Yes | 59,039 |
| 59 | flaC | P96747 | Two-component system; Flagellar assembly | Predicted | Periplasmic | No | No | Yes | 26,606 |
| 60 | secD | Q0P9G1 | Bacterial secretion system | Inferred | Cytoplasmic Membrane | Yes | No | Yes | 57,251 |
| 61 | secF | Q0P9G2 | Bacterial secretion system | Inferred | Cytoplasmic Membrane | Yes | No | Yes | 36,112 |
| 62 | secE | Q0PB41 | Bacterial secretion system | Inferred | Cytoplasmic Membrane | Yes | No | No | 6,745 |
| 63 | secY | Q0P7U3 | Bacterial secretion system | Inferred | Cytoplasmic Membrane | Yes | No | Yes | 46,050 |
| 64 | Cj1094c | Q0P9G0 | Bacterial secretion system | Predicted | Cytoplasmic Membrane | Yes | No | Yes | 10,172 |
| 65 | tatB | Q9PHT7 | Bacterial secretion system | Inferred | Cytoplasmic | No | No | No | 15,746 |
| 66 | tatC | Q9PHT8 | Bacterial secretion system | Inferred | Cytoplasmic Membrane | Yes | No | No | 27,808 |