Table 5.

Upper and lower panels: Uni- and multivariate analyses adjusted by Framingham risk factors including age, sex, hypertension, diabetes mellitus, current smoking, and dyslipidaemia

	Univariate			Multivariate (CAD RF adjusted)
	HR	95% CI	P-value	HR	95% CI	P-value
Upper panel
Left dominant
None/normal	1	Reference	Reference	1	Reference	Reference
Non-obstructive	2.76	0.77–9.92	0.1209	1.75	0.35–8.71	0.4975
One-vessel disease	16.92	5.50–52.1	<0.0001	16.27	3.81–69.4	0.0002
Right dominant
None/normal	1	Reference	Reference	1	Reference	Reference
Non-obstructive	4.8	3.02–7.63	<0.0001	3.5	2.12–5.77	<0.0001
One-vessel disease	24.43	15.9–37.5	<0.0001	15.91	9.79–25.8	<0.0001
Left dominant
LM >50%	9.02	2.71–30.0	0.0003	6.45	1.66–25.0	0.007
RCA >50%	5.34	2.19–13.0	0.0002	3.49	1.29–9.47	0.0141
Right dominant
LM >50%	4.13	2.37–7.22	<0.0001	1.35	0.73–2.51	0.3456
RCA >50%	10.33	8.16–13.1	<0.0001	5.7	4.27–7.59	<0.0001

HRs of CAD according to (upper panel) the amount of diseased vessels (one-, two-, and three-vessel disease) and (lower panel) the stenosis location for the composite outcome of all-cause mortality, non-fatal MI, and coronary revascularization in LCD or RCD compared with normal coronary arteries on CCTA.

LM, left main artery; RCA, right coronary artery; CAD, coronary artery disease; RF, risk factor; HR, hazard ratio; CI, confidence interval.