Table 1. Comparison of PIP2 and PC lipids involved in FAK binding.
Simulation | % time of binding | N L a (x i > 10%) b | N L (x i > 5%) | |||
---|---|---|---|---|---|---|
PIP2 | PC | PIP2 | PC | PIP2 | PC | |
I | 68.1 | 31.8 | 9 | 0 | 12 | 7 |
II | 88.2 | 58.4 | 8 | 1 | 13 | 17 |
III | 84.6 | 39.1 | 7 | 0 | 12 | 1 |
a N L is defined as the number of lipids that make contact over 10% or 5% of simulation time.
b The contact percentage of PIP2/PC lipids is calculated as the number of times a specific PIP2/PC lipid made contact with FAK normalized by the total number of times FAK established contact with PIP2/PC lipids.