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. 2015 Jul 17;10(7):e0132487. doi: 10.1371/journal.pone.0132487

Fig 1. Time-dependent changes of IBA1, TLR4, CB1 and CB2 mRNA in the ischemic cortex.

Fig 1

. Animals received a 30-min right middle cerebral artery occlusion. The expression of IBA1, TLR4, CB1 and CB2 mRNA in the ischemic cortex (R, right cortex) was normalized to the non- ischemic cortex (L, left cortex). (A) IBA1 and (B) TLR4 mRNAs were significantly increased up to 15 fold on day 5 and returned to control levels on day 10 post-stroke. (C) CB1R expression was slightly (<1 fold) but significantly reduced on days 1, 5 and 10. (D) CB2R mRNA was significantly increased to 10 fold on day 1, 25 fold on day 2, and 40 fold by day 5.