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. 2015 Jul 17;10(7):e0132487. doi: 10.1371/journal.pone.0132487

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Fig 7 — Rats were treated with AM1241 (2.5 mg/kg, n = 7) or vehicle (n = 7) at 5-min prior to MCAo. (A) Representing TTC histology taken at day 2 after MCAo indicates that the size of the lesion was reduced in an animal receiving AM1241. (B) The area of infarction in brain slices was quantified every 2 mm from the rostral end. AM1241 significantly reduced brain lesion (p<0.001, two-way ANOVA+ Newman-Keuls test). (C, D) Neurological tests were evaluated on day 2 post-stroke. Pretreatment with AM1241 significantly reduced (D) Bederson’s neurological scores (p = 0.011) and (C) marginally mitigated body asymmetry (p = 0.073).