Fig 5. The protective effect of curcuminon β-Lg fibrils-induced cytotoxicity of PC12 cells.

PC12 cells were incubated with or without β-Lg fibrils, obtained in the absence and/or presence of curcumin, Pb²⁺, or AFM1. The PC12 cell viability was determined using MTT assay after incubation for 4 or 8 h. Incubation with β-Lg fibrils containing curcumin significantly decreased the amount of cell death compared with β-Lg fibrils in the absence of curcumin. Data represent the means ± S.E.M (n = 3; *significantly different from control).