Fig 8. ATRA increases ADAM10 and decreases RAGE expression after I/R injury.

Both in vivo and in vitro studies showed that ATRA treatment increased ADAM10 expression. Levels of RAGE, which is cleaved by ADAM10, were low. GAPDH served as a loading control (control ratio was set to 1; n = 3 in every group, ^# P < 0.05 vs. control). Data is expressed as means ± SD.