Fig 4.
The effect of glass microspheres (24 hrs) on [Ca+2]i transients. (A) The diastolic and systolic fluorescence ratios recorded from NRVM stimulated at 0.5, 1.0,1.5 and 2.0 Hz. (B) The rate of [Ca+2]i relaxation in [Ca+2]i transients generated at 0.5, 1.0, 1.5 and 2.0 Hz. *P<0.05, n = 6 for control, n = 4 for microspheres. (C) Representative [Ca+2]i transients in control and microspheres-treated cultures (D). Panel D shows the disappearance of the arrhythmias as the stimulation rate is increased.