A, tLTP induced by 10 pairings was prevented when TRPV1 was inhibited by capsazepine (10 μm, n = 6). B, summary bar graphs show that capsazepine (10 μm, n = 6) or AMG9810 (1 μm, n = 5) prevented the 10 pairings-induced tLTP. Representative traces are the average of 15 EPSCs during baseline recording (black traces) and 50 min after STDP protocol (grey traces). Error bars represent SD. *P < 0.05; ns, non-significant.