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. 2015 May 13;593(Pt 13):2833–2849. doi: 10.1113/JP270324

Figure 8. Bidirectional eCB synaptic plasticity in a single neuron.

Figure 8

A and B, eCB-tLTP and eCB-tLTD can be induced sequentially in the same neuron. Representative experiments illustrate in A an eCB-tLTP event (induced by 10 post–pre pairings, red vertical line) followed by an eCB-tLTD occurrence (induced by 50 pre–post pairings, blue vertical line) and in B the reversed sequence (eCB-tLTD followed by eCB-tLTP). In both cases, the EPSC of the neurons returned to baseline level after the full sequence. Single EPSC amplitudes (empty grey circles) and averaged data (empty white circles) are represented.