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. 2015 May 22;593(Pt 13):2909–2926. doi: 10.1113/JP270053

Figure 10. Photostimulation of the RTN in control animals has no effect on breathing.

Figure 10

A, location of the bilateral optic fibre tips identified in control rats (Arch−; n = 5) and Arch-expressing rats (Arch+; n = 8) overlap in the ventrolateral medulla. These sites are plotted on two transverse brain sections closest to their location. The tip sites of example B are represented by the filled star. Stereotaxic coordinates (transverse planes posterior to bregma) correspond to the atlas of Paxinos & Watson (2005). B, bilateral illumination of the RTN region with green light (10 s, ∼5 mW) in an Arch− rat produced no change in breathing variables. C, group data from five Arch− animals show no effect of photostimulation of RTN with constant green light (10 s, ∼5 mW) on breathing variables in either non-REM sleep or quiet wake states (two-way repeated measures ANOVA). nREM, non-REM; RTN, retrotrapezoid nucleus