Table 2.
Characteristics of cases of esophageal eosinophilia (≥15 eos/hpf) by season
| Winter (n = 3701) | Spring (n = 4150) | Summer (n = 3607) | Autumn (n = 3066) | p | |
|---|---|---|---|---|---|
| Characteristic | |||||
| Age (yrs) mean ± SD (IQR) | 45.55 ± 16.15 (34.16–56.50) | 44.89 ± 16.49 (33.43–55.89) | 44.10 ± 16.35 (32.31–54.80) | 45.35 ± 15.83 (34.59–55.97) | 0.0008 |
| Male n (%) | 2448 (66.14) | 2644 (63.71) | 2245 (62.45) | 1961 (63.96) | 0.006 |
| Clinical symptoms/EGD indications n (%) | |||||
| Dysphagia/odynophagia | 2026 (54.74) | 2182 (52.58) | 1901 (52.70) | 1689 (55.09) | 0.06 |
| Heartburn | 1490 (40.26) | 1755 (42.29) | 1476 (40.92) | 1268 (41.36) | 0.32 |
| Chest pain | 97 (2.62) | 154 (3.66) | 130 (3.60) | 106 (3.46) | 0.04 |
| Abdominal pain/dyspepsia | 901 (24.34) | 1076 (25.93) | 976 (27.06) | 762 (24.85) | 0.04 |
| Nausea/vomiting | 193 (5.21) | 250 (6.02) | 211 (5.85) | 189 (6.16) | 0.33 |
| Weight loss | 50 (1.35) | 67 (1.61) | 71 (1.97) | 42 (1.37) | 0.13 |
| Histological features | |||||
| Maximum eosinophil count, mean ± SD (IQR) | 36.17 ± 23.64 (20–48) | 37.45 ± 25.45 (20–50) | 37.44 ± 24.17 (20–50) | 36.96 ± 24.23 (20–50) | 0.07 |
| Eosinophil microabscesses | 867 (23.43) | 1017 (24.51) | 862 (23.90) | 703 (22.93) | 0.44 |