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A). Pulmonary metastasis obtained after completion of vaccination (patient CCS-8). Numerous plasma cells (with characteristic eccentric nuclei and cartwheel-like chromatin pattern) are admixed with the tumor cells. B). Pre- and post-vaccination sera samples were diluted 1:100 and evaluated for reactivity against recombinant tTPA, angiopoietin-1, and angiopoietin-2 in ELISAs.
