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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Shock. 2015 Aug;44(2):137–142. doi: 10.1097/SHK.0000000000000394

Figure 1. α-enolase increases the surface expression of ICAM-1 on HMVECs.

Figure 1

The mean fluorescent intensity (MFI) of intercellular adhesion molecule-1 (ICAM-1) surface expression is depicted as a function of treatment group. As compared to media-treated control HMVECs, the positive control endotoxin (LPS [2μg/ml]) caused significantly increased ICAM-1 surface expression on HMVECs on both panels. Panel A demonstrates the effect of α-enolase on ICAM-1 surface expression which was significantly increased at 50 μg/ml (*=p<0.05 vs. media-treated HMVECs, n=5). Panel B shows the effect of thrombin stimulation on the surface expression of ICAM-1 on HMVECs. In comparison to media-treated controls thrombin significantly increased ICAM-1 surface expression at 5–10 U/ml (*=p<0.05 vs. media treated HMVECs, n=5).