Table 3.

Vancomycin dosing and monitoring parameters for those with culture-confirmed gram positive infections

	TDM (n = 66)	CTRL (n = 79)	P value
Reached Initial Target Trough, n (%)	53 (80)	33 (42)	<0.001
Time to Initial Target Trough (days), median (IQR)	3 (2,3)	5 (2,7)	<0.001
Initial target trough
15–20 mg/L, n (%)	33 (50)	52 (66)	0.1
10–15 mg/L, n (%)	33 (50)	27 (34)	0.1
Loading dose, n (%)	3 (5)	0	0.54
Initial dose
1.0 g q12hr, n (%)	28 (42)	63 (80)	<0.001
1.0 g q8hr, n (%)	12 (18)	1 (1)	0.001
Other, n (%)	26 (40)	14 (19)	0.005
No dose adjustment, n (%)	21 (32)	37 (48)	0.06
Number of troughs drawn per patient, median (IQR)	1 (1,4)	2 (1,4)	0.02
Mistimed troughs drawn per patient, median (IQR)	0 (0,2)	1 (0,2.5)	0.002
Total VAN Dose (g), median (IQR)	10 (7,20)	11 (7,21)	0.29