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. 2015 Jul 19;4:364. doi: 10.1186/s40064-015-1146-9

Table 4.

Analysis of clinical outcomes for all culture confirmed gram positive infections and the MRSA infection subset

Outcome Univariate Multivariate
TDM CTRL P-value TDM vs. CTRL P-value
Median (IQR) Median (IQR) Hazard Ratio (95% CI)
All gram positive infections
 Inpatient length of stay (days) 7 (3,10) 14 (8,26) 0.03 1.41 (1.08–1.83) 0.01
 Inpatient length of VAN Treatment (days) 4 (2,4) 7 (5,10) <0.001 1.5 (1.15–1.95) 0.003
 Time to clinical stability (days) 4 (3,5) 8 (3,7) 0.004 1.51 (1.08–2.11) 0.02
 Time to normal WBC count (days) 4 (2,10) 6 (3,13) 0.14
MRSA Subset
 Inpatient length of stay (days) 7 (4,20) 16 (7,38) 0.035 1.89 (1.08–3.3) 0.03
 Inpatient length of VAN treatment (days) 5 (3,12) 8 (5,16) 0.034 2.52 (1.38–4.6) 0.003
 Time to clinical stability (days) 4 (3,4) 6 (4,10) 0.013 2.69 (1.27–5.7) 0.01
 Time to normal WBC count (days) 4 (2,5) 5 (2,6) 0.617