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. 2015 Jun 19;6(8):553–561. doi: 10.1007/s13238-015-0176-y

Figure 4.

Figure 4

Mesp2-null embryos exhibited defective segmentation in somitogenesis. (A) In Mesp2 (−/−) embryos at E9.5, segmentation of somites is defective, while differentiation into dermomyotome (DM) proceeds. Compared to wildtype (+/+) embryos at the same developmental stage (B), Mesp1 (−/−) embryos showed differentiation into dermomyotome and sclerotome with segmentation exhibiting reduced segmental width (indicated by the width of brackets) (C and D). DM, dermomyotome. Bars, 100 μm. Adapted from Saga (1998) with permission